Decreased Perivascular Fibrosis but Not Cardiac Hypertrophy in ROCK1
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چکیده
Yoshiyuki Rikitake, Naotsugu Oyama, Chao-Yung C. Wang, Kensuke Noma, Minoru Satoh, Haploinsufficient Mice − +/ Decreased Perivascular Fibrosis but Not Cardiac Hypertrophy in ROCK1 Print ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 2005 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation doi: 10.1161/CIRCULATIONAHA.105.584623 2005;112:2959-2965; originally published online October 31, 2005; Circulation. http://circ.ahajournals.org/content/112/19/2959 World Wide Web at: The online version of this article, along with updated information and services, is located on the
منابع مشابه
Decreased perivascular fibrosis but not cardiac hypertrophy in ROCK1+/- haploinsufficient mice.
BACKGROUND Rho GTPase and its downstream target, Rho-associated kinase (ROCK), have been implicated in diverse cardiovascular diseases such as cardiac hypertrophy. However, pharmacological inhibitors of ROCK are not entirely specific, nor can they discriminate between the ROCK isoforms ROCK1 and ROCK2. To determine the specific role of ROCK1 in the development of cardiac hypertrophy, we generat...
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تاریخ انتشار 2005